He signed with the Indianapolis Colts as an undrafted free agent after the 2014 NFL draft, and has also been a member of the Seattle Seahawks, BC Lions, Ottawa Redblacks, and Saskatchewan Roughriders.

[2] He played quarterback, running back and wide receiver in the Eagles' split-back veer offense.

[6] Purifoy's problems off the field may have contributed to a slip from a late draft pick to an undrafted free agent.

Both performed well and cutting either would be difficult, so the Colts traded Burley to the Seattle Seahawks for a sixth round draft pick.

[12] Purifoy was claimed off waivers by the Seattle Seahawks on November 28, 2014, but was waived after a failed physical on December 1, 2014.

[13][14] Whilst a free agent, Purifoy was suspended by the NFL for the first ten weeks of the 2015 season, most likely for violating the substance abuse policy.

He was, however, deemed ineligible for rookie of the year consideration based on the fact that he had dressed for an NFL regular season game in the past.