Louis Picotte (May 4, 1780 – May 7, 1827) was a farmer, merchant and political figure in Quebec.
He represented Saint-Maurice in the Legislative Assembly of Lower Canada from 1820 to 1824 as a member of the Parti canadien.
He was born in Rivière du-Loup (later Louiseville), the son of Jean-Baptiste Picotte, an Acadian refugee, and Hélène Jarlais.
Picotte was a voyageur in the Northwest with McTavish, Frobisher and Company.
Picotte established a butcher shop in Trois-Rivières around 1813.