Louis Samain (July 4, 1834 – October 24, 1901) was a Belgian sculptor.
Samain was born in Nivelles, and studied at the Académie Royale des Beaux-Arts in Brussels under Louis Simonis.
After winning the Belgian Prix de Rome, he lived for a time in Italy.
In 1889, he was awarded a gold medal at the Paris Exposition Universelle, and in 1895 his work was shown at the Société des Artistes Français in Paris.
He died in Ixelles.