After travelling into the interior as far as Bathurst, Mrs Meredith returned to the coast and lived at Homebush for around a year,[3] and where she bore a son.

In 1860 she published Some of My Bush Friends in Tasmania which contained elaborate full-colour plates printed by the new chromolithography process.

Meredith was the author of two novels, Phoebe's Mother (1869), which had appeared in the Melbourne weekly The Australasian in 1866 under the title of Ebba, and Nellie, or Seeking Goodly Pearls (1882).

[3] Meredith took great interest in politics, her husband Charles being a Member of the Tasmanian Legislative Council for several terms between the mid-1850s until just before his death in 1881.

She was an early member of the Society for the Prevention of Cruelty to Animals and influenced her husband to legislate for preservation of native wildlife and scenery.

Hall and Mather[9] suggest that Meredith, nine years her senior, may have preceded Louisa Elizabeth How as the first woman photographer in Australia.

Vivienne Rae-Ellis cites the subtitle of Meredith's 1861 Over the Straits; With Illustrations from Photographs, and the Author's Sketches., to note that photographs she made documenting her travels in Victoria in the 1850s were copied for the drawings, alongside her freehand sketches, reproduced for engravings that illustrate the book, as was usual in days before photomechanical reproduction.