[6] Traders and missionaries often visited the area, and by 1854 Euro-American farmers began moving nearby, establishing homes.

By 1866, following the Civil War, the government moved the Confederated Tribe of Peoria to Oklahoma,[6] and the land they once occupied was sold to settlers.

From 1868 to 1870, the settlement of Little St. Louis grew to include businesses and churches, and a railroad depot was to be completed.

As a town near the border, there remained conflicts between Kansas Jayhawkers and Missouri Raiders.

In addition, the railroad tracks running through the community divided it into north and south areas.

Circa 1875, many businesses and homes were moved from north of the railroad to the south, and formed what was to become downtown Louisburg.

[7] In October 1912, an unsolved murder in the community took place as the town's postmaster at the time, George McElheny, was shot twice by a 12-gauge shotgun at his home.

In later years, the murder was almost forgotten until Joe Towne, one of the community leaders, grew interested in the subject and studied it and interviewed those who remembered the tragic situation and wrote true crime novel, "Tongues on Fire".

Because of increased truck traffic from Missouri on K-68 through town, Louisburg was contacted by the State of Kansas about needing an inspection station.

As a solution, the Little Round House was moved to Louisburg in the 1930s to serve as a border checkpoint office.

[8] In 2005, The Little Round House was moved from its original location to the Louisburg City Lake, and has been restored by the community due to its historical value to the town.

Also located at Lewis-Young Park is the Powell Observatory, which was built in 1984 by members of the Astronomical Society of Kansas City.

The observatory's telescopes include one of the largest in the region, which is also one of the few in the nation of its size that is made available for public viewing.

The observatory regularly schedules viewings available to the public, and provides shows that are intended to educate individuals about astronomy.

Near Louisburg is Rutlader Outpost, which has an RV park for those who camp and an antique store for shopping.

The Louisburg Cider Mill holds several special events throughout the year, including Ciderfest in the fall.

[12] Another unique attraction near Louisburg is Cedar Cove Feline Conservatory & Sanctuary.

The big cats such as Siberian tigers, who reside in this conservatory, aid in teaching people about the wild.

In addition, the conservatory allows people to learn how to aid these cats and their relatives who still live afar in the wild.