It serves students of grades 9 to 12 in the community of Louisburg and nearby rural areas.

The Wildcats are classified as a 4A school, the third-largest classification in Kansas according to the Kansas State High School Activities Association.

In 2010, the Louisburg High School football team was undefeated and won the state championship.

The boys track and field team won the 4A state championship in 2011 and 2021.

[6] The Louisburg High School Marching Wildcat Band has participated in many events, including the 2018 Rose Parade on New Year's Day in Pasadena, California.