Louisburg is an unincorporated community in Grant County, Wisconsin, within the town of Jamestown.

Louisburg Creek flows through the area.

Louisburg is located 1.5 miles east of Kieler, 2.5 miles southeast of Dickeyville, 8 miles west of Cuba City and 10 miles northeast of Dubuque, Iowa.

There are approximately 30 residences and 7 rental properties in Louisburg which are home to an estimated 110 people.

This article about a location in Grant County, Wisconsin is a stub.