Among her extended family members were nieces Rose Post Howard,[3] who married Thomas H. Howard (a descendant of Peter Stuyvesant),[4] and Margaret Van Alen Bruguiére, who married James Laurens Van Alen (a grandson of William Backhouse Astor Jr. and Caroline Schermerhorn Astor).

Louise died at the Hotel Ritz in Paris on August 21, 1926, following "a short illness caused by complications setting in from a slight throat infection.

"[9] Frederick returned to the United States with Louise's body aboard the White Star Liner Homeric.

A section of the baggage room on the lower deck was made into a chapel with wreaths, floral arrangements, and the spiral staircase leading to it draped with black.

During their marriage, which lasted nearly fifty years, Louise and Frederick made their New York City home at several locations.

During World War I, she joined wealthy neighbors to equip, clothe, and arm a Hyde Park Home Defense Company of sixty-five men.

[13] Charities that benefited from her will at the time of her death included legacies in the sum of $10,000 each bequeathed to the New York Orthopedic Dispensary and Hospital, the Woman's Hospital, the Children's Aid Society, the American Society for the Prevention of Cruelty to Animals, the Stanton Street Helping Hand Association, and the New York Women's League for Animals, Inc.

The largest single bequest was $300,000, to establish a trust fund for her Anthony Home, Inc., a model residential building for working women.