It proceeds east, immediately crossing the Union Pacific Railroad (UPRR) tracks, and makes a zigzag through the tiny community of Morrow.

Leaving Morrow, LA 107 continues eastward along Dry Bayou for about 4.6 miles (7.4 km) to a point known as Big Cane.

Here it intersects LA 361 and turns north to follow that highway briefly before resuming its eastward course.

LA 107 enters Cottonport on Choupique Lane where it makes a zigzag to the west and back to the north.

LA 1 heads south through Simmesport and New Roads on the way to Baton Rouge, the state capital.

From this junction, LA 107 (also known in these parts as Old Marksville Highway) takes a northwest course through Kolin to Shady Oaks.

Ramps from the service roads provide access to the expressway, which continues southwest into Alexandria and northeast out of Pineville, where US 167 and LA 28 separate and head toward Winnfield and Jonesville, respectively.

[8][9][10] LA 107 was created with the 1955 Louisiana Highway renumbering,[11] and its route has seen several minor changes, most significantly in Marksville and at the northern terminus in Pineville.

[12] Improvements to LA 1 during the early 1970s created a more direct alignment through Marksville, and LA 107 was re-routed to follow the portion between South Preston Street and South Main Street, eliminating a zigzag.

[15] In March 1963, the Pineville Expressway, temporarily designated as LA 3026, was opened northward as far as Shamrock Street.

[5][7] Other improvements caused further minor alterations in the route, including the smoothing of both a zigzag south of Dupont and a curve at Shady Oaks, and a change of connector road in Morrow.

[20][21] In March 2000, the current bridge over the Red River at Moncla - the third constructed at this location - was opened on the southwest side of the previous bridge, which was then demolished, necessitating a slight realignment of LA 107 (and concurrent LA 115) on the approaches.