[2] Former South Carolina Governor Robert Y. Hayne was named the first president of the Louisville, Cincinnati and Charleston, and other board members included John C. Calhoun and Robert Mills.
[3] Gadsden was a proponent of a Southern transcontinental railroad and was convinced it would be necessary to purchase a strip of territory along the Gila River from Mexico to make that project a reality.
[5] In 1844, the Louisville, Cincinnati and Charleston Railroad purchased the stock, road, and corporate privileges of the South Carolina Canal and Rail Road Company for $2.4 million.
[5] In 1853, the company constructed a 1.8-mile (2.9 km) line, mainly a bridge over the Savannah River, from Hamburg, South Carolina to Augusta, Georgia.
[5] The South Carolina Rail Road Company, in turn, was sold at foreclosure on November 1, 1881 to the organizers of The South Carolina Railway Company, incorporated under the general laws of South Carolina, October 17, 1881, amended by act of December 24, 1885.