In 1178, King Sancho I of Portugal having discovered that the Moors of Lisbon were allied to groups in Loures, and came to the territory with a Templar force to confront those peoples.

[2] In Loures, the Templar lands passed into the hands of this religious order, eventually constructing a new Church over the ruins of the 4th-century temple, located alongside the Christian cemetery that existed there.

[2] The Chapel of Nossa Senhora da Saúde was built during this era: in 1598, the Plague devastated the capital, and for five years on it spread across the country (resulting in the death of approximately 80,000 victims).

[2] Some families brought with them the image of Our Lady of Health, and raised a church, in order to defend themselves of the Plague: by 1604 the threat had passed, and no cases of the disease were discovered within the territory.

[4] Loures borders the municipalities of Odivelas, Sintra, Mafra, Arruda dos Vinhos, Vila Franca de Xira and Lisbon.

[5] The municipality is traditionally divided in three areas: the rustic one, to the north (the parishes of Lousa, Fanhões, Bucelas, Santo Antão do Tojal and São Julião do Tojal), the urban one, to the south (Frielas, Loures and Santo António dos Cavaleiros) and the urban-industrial, to the east (Apelação, Bobadela, Camarate, Moscavide, Portela de Sacavém, Prior Velho, Sacavém, Santa Iria de Azóia, São João da Talha and Unhos).

Administratively, the municipality is divided into 10 civil parishes (freguesias):[9] From these, both Loures and Sacavém are cities, and Bobadela, Bucelas, Camarate, Moscavide, Santa Iria de Azóia, Santo António dos Cavaleiros and São João da Talha are towns.