The series aired four episodes every Saturday on MBC TV from February 23 to April 27, 2019.

[2][3] Yoon Ma-ri (Park Ha-na/Park Han-byul) is in an unhappy marriage with Kang In-wook (Ryu Soo-young), an abusive, and obsessively possessive husband who is also a chaebol.

She meets Seo Jung-won (Ji Hyun-woo), a kind-hearted plastic surgeon.

After seeing the abuse she receives, Seo Jung-won operates on her face to help her start a new life with a new identity after which she develops feelings for the surgeon, and he for her.

Ahead of its premiere, netizens were comparing Love in Sadness with the 2018 SBS TV weekend drama Let Me Introduce Her.