The song was a massive success worldwide and was the longest-running number-one single of 2008 in the United States, spending ten consecutive weeks atop the Billboard Hot 100.

It is a crunk song that contains electronic elements such as 808-style handclaps and an arpeggiated ostinato note sequence instead of a chord progression.

Flo Rida has sexually charged (but not explicit) lyrics, for example he refers to a woman's buttocks as "birthday cakes" which "stole the show".

"Low" is written in common time with a moderate tempo of 128 beats per minute while T-Pain's vocal range spans nearly two octaves from B♭2 to F♯4.

Thematically, the song describes a sexually desirable girl dancing in a club, and the singer's efforts to hook up with her, primarily by flaunting displays of cash.

It also contains cameos from Rick Ross, DJ Khaled, Cool & Dre, Briana Evigan, Torch and Gunplay of Triple C's and Jermaine Dupri.

The song became either a hit in most of European countries, reach the top ten like in Finland (no.9), in Denmark (no.9) or again in Belgium (Flanders charts) (no.7).

On October 23, 2012, the cast of The Big Bang Theory made a flash mob during the live taping of an episode, which featured the song as well as others.

A year later, in 2020, the American grocery chain Kroger and their subsidiary stores began to use the song's chorus for a series of animated ads, appropriately highlighting coupons and low prices.

[88] Also, a parody of the song highlighting price drop was used in the 2021 Lazada 11.11 TV commercial featuring K-Pop boy group Seventeen in the ASEAN region, where it was sung in Indonesian, Tagalog, Thai, Vietnamese, and English.