The Lowell and Lawrence Railroad was a small independent railroad that was chartered in 1846 to build a rail line linking the two giant Merrimack River Valley cities of Lowell, Massachusetts to Lawrence, Massachusetts.
Construction began in 1846 and passed through Tewksbury and West Andover and met the B&M main line in South Lawrence.
The line opened in 1848 and began running both freight and passenger service between the two cities.
By the time the two lines fell under control of the Boston and Lowell, the entire Wye was called Tewksbury Jct.
Between 1895 and 1900, service ended on the line from its start at the Bleachery in Lowell to Wamesit in Tewksbury where the B&M and the L&L shared a station.