It is located on the west bank of the Missouri River in Lyman and Stanley counties in central South Dakota in the United States.

The Lakota, or Western Teton/Tituwan Sioux, consisting of the Oglala, Miniconjou, Sicangu, Sihasapa, Two Kettles, Hunkpapa, and Itazipco, traditionally ranged from lands east of the Missouri River valley to the Rocky Mountains.

In 2013, the tribe requested that the KELO-TV station find a new site for a transmission tower on Medicine Butte that had fallen.

The Lower Brule Sioux Tribe is a sovereign nation defined by its government-to-government relationship with the United States.

The tribe has contracted several aspects of self-government under the 1975 Indian Self Determination and Education Assistance Act, PL 93-638.

The tribal council chairman serves as the chief executive officer and administrative head of the tribe.

The operation of the dam caused flooding of the Lower Brule community and surrounding bottomlands in the heart of the reservation.

It provided for payments to the tribe of amounts beginning in 1998 and annually until the aggregated of $39.3 million had been accumulated in the trust fund.

Since establishment of the trust fund, the authority has supervised development of the administration building and community center located in Lower Brule.

The tribe has established the Buffalo Interpretive Center, providing insight into the people and their customs.

The Lower Brule Sioux Tribe is a member of the West Central Rural Electric Cooperative.

Lake Sharpe serves as a virtually unlimited water source for the Lower Brule community.

The Lower Brule Sioux Tribe, in coordination with the Indian Health Service, operates a solid waste collection and transfer facility.

The tribe is planning to develop additional market-rate housing to meet the needs of tribal residents who do not satisfy the low-income requirements.

The tribe’s $5.8 million Veteran's Memorial Community Center has a swimming pool, full-size basketball court, weight and exercise rooms and a large kitchen.

The Lower Brule IHS Service Unit operates a dental clinic, medical clinic and conducts several outreach programs, which provide services to the members of the Lower Brule Sioux Tribe on a regular basis, and to anyone in an emergency.

There are charter buses and limousines serving patrons of the Golden Buffalo Casino, and Greyhound Lines terminals are located in Chamberlain and Pierre.

River City Transit runs a daily bus/van transportation service between Lower Brule and Pierre.

In addition, the tribe is involved in a video-cultural program in which students, teachers and elders document important cultural activities and histories.

Jim Miller, a spiritual leader and Vietnam War veteran, organized a group ride by horseback in 2012 following a vivid dream.

They traveled from South Brule to Mankato, Minnesota, reaching it by December 26, the 150th anniversary of the largest mass execution in United States history.