Lowndesville is a town in Abbeville County, South Carolina.

[6] According to the United States Census Bureau, the town has a total area of 0.77 square miles (2.0 km2), all land.

The racial makeup of the town was 76.51% White, 20.48% African American, and 3.01% from two or more races.

35.5% of all households were made up of individuals, and 15.8% had someone living alone who was 65 years of age or older.

About 22.9% of families and 28.0% of the population were below the poverty line, including 80.0% of those under the age of eighteen and none of those 65 or over.