Lubombo is a region of Eswatini, located in the east of the country.

It borders all three other regions: Hhohho to the north, Manzini to the west, and Shiselweni to the south.

Geographically, the region is dominated almost entirely by the Lubombo Mountains.

The Lubombo District is the easternmost of the four regions of Eswatini.

Each inkhundla is headed by an indvuna yenkhundla or governor with the help of bucopho.