He was born in Youngstown, Ohio, but lived nearly his entire life in Coraopolis, Pennsylvania, just west of Pittsburgh.

[1] DiMeolo was a guard and captain on the 1929 University of Pittsburgh team that was undefeated before losing in the 1930 Rose Bowl to USC.

[3] When the Pittsburgh Pirates joined the NFL in 1933, DiMeolo was rumored to be the leading candidate to become the team's initial player-coach.

[1] He joined the navy during World War II and served as a physical instructor, rising to the rank of lieutenant commander.

[1] After leaving the navy, DiMeolo worked in the Pennsylvania state Department of Commerce, before losing his position due to a change in the political party running the government.