Luca Brandolini, CM (born 25 December 1933) is an Italian prelate of the Roman Catholic Church who served as Bishop of Sora-Aquino-Pontecorvo from 1993 to 2009.

On 29 October 1987, Brandolini was appointed Pro-Vicar General of Rome and Titular Bishop of Urusi by Pope John Paul II.

He received his episcopal consecration on the following 7 December from Ugo Cardinal Poletti, with Archbishop Ennio Appignanesi and Bishop Plinio Pascoli serving as co-consecrators.

Brandolini disapproved of Pope Benedict XVI's Summorum Pontificum, saying to La Repubblica, "I can't fight back the tears.

This is the saddest moment in my life as a man, priest and bishop...It's a day of mourning, not just for me but for the many people who worked for the Second Vatican Council.