Lucanthone is a drug used to treat parasitic diseases such as bilharziasis[1] and schistosomiasis[2] It is a prodrug and is converted to the active metabolite hycanthone.

[3] Hycanthone binds to acetylcholine receptors in the worm[4] and results in increased sensitivity to stimulation by 5-HT causing increase in motility, paired worms are separated and reproduction is stopped.

It causes damage of the integument and vitelline duct.

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