Poston's research is about disorders of pregnancy especially when caused by maternal nutrition, and how children's lives can be affected.
[3] Poston founded and is Director of the Maternal and Fetal Research Unit which undertakes large-scale clinical trials.
[4] Her early research was into the control of the circulatory system of the placenta showed its relevance to pre-eclampsia.
She led a clinical trial that changed medical practice through demonstrating that anti-oxidant supplements did not prevent pre-eclampsia.
[6] In 2021 Poston was President of the International Society for Developmental Origins of Health and Disease.