She was a recurring character on ABC Family's Melissa & Joey (2010–2012), starred in the Hulu sitcom Deadbeat (2014–2015), and was a main voice actor and executive producer of the FXX animated comedy Little Demon (2022).
In 2007, DeVito starred as the non-speaking autistic title character in the play Lucy at the Ensemble Studio Theater.
[6] Her first major movie role was the 2009 film Leaves of Grass;[7] later that year DeVito starred alongside her mother in the off-Broadway play Love, Loss, and What I Wore, adapted by Nora and Delia Ephron, at the Westside Theatre.
[9] In 2016, DeVito performed the role of Annelle Dupuy-Desoto in Steel Magnolias at the Bucks County Playhouse in New Hope, Pennsylvania.
This production was directed by Marsha Mason, and also starred Patricia Richardson, Elaine Hendrix, Jessica Walter and Susan Sullivan.