[3] Ludwigslust station is located in the north of the built-up urban area at kilometre 170.8 of the Berlin–Hamburg line.

It is connected to the town centre by Bahnhofsstraße (“station street”), which runs as a two-lane cobble-stoned avenue parallel with the Ludwigslust Canal.

The street formerly continued towards Wöbbelin, but the level crossing at the south side of the station was closed in 1996 during upgrading of the line.

The architectural design in its original state included avant-corps at its corners, had restrained ornaments and a bright shiny colour.

The entrance building had to be extended to handle the construction and commissioning of additional railway lines.

All platforms are accessible from a pedestrian underpass, which also connects Bahnhofsstraße with Wöbbeliner Straße on the south side of the station.

These were built in 1912, including the freight office, the round roundhouse with its turntable and a water tower.

[7] Although Ludwigslust was still the summer residence of the dukes of Mecklenburg, the direct connection to Schwerin via Holthusen did not open until 1 October 1889.

As early as 1898, the railway administration in Schwerin wanted an additional island platform for ensuring connections to Hamburg and Berlin.

The need for extensions was also significant in 1899, when some freight trains had to be left on the open line due to lack of space.

Thus, earth was taken from between Ludwigslust and Eldena and heaped on the station premises and laid under the railway tracks.

A goods shed that had been converted in 1890 was demolished in 1911 to make room for new tracks and replaced by a new building in 1912.

[5] On 1 October 1913, a connecting curve was put into operation southeast of the station between the lines to Dömitz and Parchim, under the control of signal boxes "Lvn" and "Lvs", enabling freight trains to bypass the station and to avoid Prussian state railways charges for the use of the line.

Deutsche Post opened a packet handling facility at the station on 27 May 1962 and, from 31 May 1964, all parcels between the three northern districts of German Democratic Republic, Neubrandenburg, Rostock and Schwerin and the Federal Republic of Germany were handled here.

From German reunification until 1996/1997, the line between Berlin and Hamburg was upgraded and has been operated with Intercity-Express services since 1997.