The station is located about 1.3 kilometres from the city centre on the eastern edge of the town of Wittenberge.

Two island platforms, each with a length of 405 m and a height of 76 cm, extend towards the north from the centre of the entrance building.

From 1870 trains also ran from here on a branch of the Berlin-Hamburg Railway, that led over the river Elbe near Dömitz and via Dannenberg to Buchholz.

The running speed through the station was raised from 30 to 160 km/h; an increase to 197 km/h, which was also considered, would have required the control of active tilting technology by the train safety system, LZB, but this was not put into practice.

The opening of the rebuilt station took place on 24 August 2004 in the presence of the German chancellor, Gerhard Schröder.