Due to the war in Donbas, the university's faculty and students evacuated the area in September 2014, and classes resumed in Rubizhne, another city in Luhansk Oblast.

Associate Prof. Fedir Dmitrovich Povelitsya, PhD, who led the institute from 1960 to 1963, was a graduate of the Kharkiv National Medical University and had also fought in World War II.

The campus has a modern library, a sports complex with fitness centre, tennis courts and cricket pitch, and three multi-storey student residences with Internet access.

The total area of all campus buildings is 73,957m² — including classroom facilities, 18,172m²; training and support, 15,870m²; utility services, 25,135m²; and residences, 14,870m².

The university offers interns the opportunity to specialize in any of 25 areas: Some well-known LSMU graduates include Raisa Bogatyrova, an obstetrician-gynaecologist and a former Ukrainian Minister of Health; the late Vladimir Sergeevich Zemskov, an internationally famous oncologist and surgeon in Kyiv; the late Valery K. Ivchenko, a trauma surgeon who was himself rector of LSMU from 2003 to 2014; and Tatiana Tkachuk, a specialist in gynaecological oncology who has authored numerous scientific papers.