In 1919, training courses for teachers were organized at Melitopol Non-Classical Secondary School.

In the summer of 1941, students and teachers of the university were drafted into the Red Army following the Nazi invasion of the Soviet Union.

Since 1990, a number of new departments have been organised, including the Socio-Humanitarian and Philological Faculties.

[2] In 2000, the Institute received university status by the decree of the Cabinet of Ministers of Ukraine.

[2] The university was renamed in honour of Bohdan Khmelnytsky in 2009, changing from Melitopol State Pedagogical Institute to Bohdan Khmelnytsky Melitopol State Pedagogical University.