Comencini's 1953 Pane, amore e fantasia, with Vittorio De Sica and Gina Lollobrigida, is considered a primary example of neorealismo rosa (pink neorealism).

[3] Also set in World War II, but devoted to the Italian partisans, is La ragazza di Bube (1963).

In the same year, he directed the feature film Lo scopone scientifico, a dark comedy with Sordi and Silvana Mangano.

In 1975, he released the mystery La donna della domenica, featuring Marcello Mastroianni, Jacqueline Bisset and Jean-Louis Trintignant.

Comencini's subsequent works were characterized by the presence of famous Italian actors of the time: Ugo Tognazzi in Il gatto (1977), or Nino Manfredi in his episode of Basta che non si sappia in giro.