Frulli died in 1837, and Gregori then worked for Prince Pignatelli of Monteleone, and he traveled throughout Italy, including studying in Milan and Naples.

Minardi was a major proponent of the Purismo movement, which rejected the popular neoclassicism and aimed to emulate Quattrocento artists such as Fra Angelico and Pietro Perugino.

Gregori was also inspired by Purismo's focus on a return to religious and devotional imagery, in contrast to increasingly secular trends.

Edward Sorin, who was visiting the papal court, to be artist in residence at the University of Notre Dame, where he stayed for seventeen years.

The decoration of the Main Building continued in 1890 with the interior of the dome depicting Religion surrounded by Philosophy, History, Science, Fame, Music and Poetry.

[5][6] His twelve murals, such as Columbus Coming Ashore, were covered in January 2019, following an announcement by the president of the Notre Dame that the action was being taken because the artworks "depict Native Americans in stereotypical submissive poses before white European explorers...