Luigi Lavitrano (7 March 1874 – 2 August 1950) was an Italian cardinal of the Catholic Church who served as Archbishop of Palermo from 1928 to 1944, and as prefect of the Sacred Congregation for Religious from 1945 until his death.

Born in Forio, Lavitrano lost his entire family in an earthquake in 1883 that devastated the island of Ischia.

Pope Pius XI created him Cardinal-Priest of San Silvestro in Capite in the consistory of 16 December 1929.

Lavitrano, who once scolded Italian Catholics for their religious negligence,[1] was one of the cardinal electors who participated in the 1939 papal conclave that selected Pope Pius XII.

After resigning as Palermo's archbishop in December 1944, he was made Prefect of the Sacred Congregation for Religious in the Roman Curia on 14 May 1945.