Exposito spent his 2010 season playing for the Portland Sea Dogs leading the team with 94 RBI.

[1] On June 8, 2011, Exposito was called up to the Red Sox as insurance after starting catcher Jarrod Saltalamacchia became ill; he filled the roster spot of Bobby Jenks, who was placed on the disabled list.

To make room for Exposito on the 40-man roster, the Orioles designated infielder Josh Bell for assignment.

Exposito signed a minor league contract with the Detroit Tigers on January 9, 2014, and was assigned to Triple–A Toledo Mud Hens, playing for them in 29 games.

Exposito signed with the Bridgeport Bluefish of the Atlantic League of Professional Baseball for the 2016 season, but instead announced his retirement on April 8, 2016.