Luis Fernando Muriel Fruto (born 16 April 1991) is a Colombian professional footballer who plays as a forward for Major League Soccer club Orlando City and the Colombia national team.

He made his senior debut in June 2012, in a World Cup qualifying match against Ecuador, and scored his first goal the following year, netting against Guatemala.

Having spent his formative years with Atlético Junior, Muriel joined Colombian Primera A side Deportivo Cali in January 2009.

[14] The club achieved promotion to La Liga for the first time in 35 years but it was an unsuccessful spell for Muriel, as he made only seven appearances for the season and failed to score.

[9] His form during the course of the season garnered the attention of A.C. Milan and Internazionale, with both clubs making official offers to sign him, but Muriel confirmed that he would be returning to Udinese.

[19] Muriel's poor physical condition upon his return to Udinese drew the ire of Francesco Guidolin, with the club manager insisting that he needed to lose 5 pounds (2.3 kg), despite the player scoring four goals against Arta Cedarchis in a pre-season friendly.

[23] By the conclusion of the season, he had contributed a return of 11 goals in 22 Serie A appearances, despite having missed nearly four months of football because of a hairline fracture of his left femur.

[27] In spite of his struggles with Udinese, Sampdoria completed the double loan signings of Muriel and teammate Andrea Coda on 22 January 2015, with an obligation to purchase both players at the end of the season for a combined sum of €12m.

[30][31] He made his debut on 19 August, starting in a 1–1 draw with Espanyol and scored his first goal for the club on 17 September, netting the winner in a 1–0 victory over Girona.

[32][33] Following a disappointing debut campaign, in which he only scored 9 goals in 46 appearances, Muriel found himself behind Wissam Ben Yedder and new club signings André Silva and Quincy Promes in the pecking order for Sevilla the following season.

[41][42] On 21 June 2019, after a successful loan spell with Fiorentina, Muriel returned to Serie A after signing with Atalanta in a permanent deal worth a reported €18 million.

On 15 February 2024, Major League Soccer club Orlando City announced the signing of Muriel as a Designated Player on a three-year contract.

[45] Muriel only managed five goals across all competitions in his first season with Orlando City, and he spoke about how he struggled to adapt to the new league, describing 2024 as a "transition year".

[57] In his youth, Muriel was often praised in the media for his precocious performances during his early career in Italy,[58] which led him to win the Serie A Best Young Revelation Award in 2012.

[59] Several footballing figures in Italy, such as manager Massimiliano Allegri, have recognised Muriel for his speed and technique on the ball, as well as the potential which he already demonstrated as a youngster;[60] his former Udinese teammate Antonio Di Natale even compared him to Alexis Sánchez in 2013.