Luis Fernando Patiño Arzuza (born October 26, 1999) is a Colombian professional baseball pitcher in the San Diego Padres organization.

He has previously played in Major League Baseball (MLB) for the Tampa Bay Rays and Chicago White Sox.

On July 2, 2016, Patiño signed with the San Diego Padres as an international free agent.

In a start against the Oakland Athletics on April 11, 2022, Patiño was removed with an oblique strain after 13 pitches.

[16] On August 1, 2023, Patiño was traded to the Chicago White Sox in exchange for cash considerations.