He has previously played in MLB for the San Diego Padres, Milwaukee Brewers, Boston Red Sox, and Seattle Mariners.

[2] In 2015, he played for the Low–A Tri-City Dust Devils and the Single–A Fort Wayne TinCaps, posting a combined .299 batting average with no home runs and 17 RBIs in 61 total games between the two teams.

[2] Urías played primarily in 2016 for the High–A Lake Elsinore Storm, for whom in 120 games he batted .330 with five home runs (his first in the minor leagues), 52 RBI, a .397 OBP, and an .836 OPS.

In 2017, he played for the San Antonio Missions of the Double–A Texas League, where as he split his time between second base and shortstop he posted a .296 batting average with three home runs, 38 RBI, a .380 slugging percentage, and a .778 OPS.

[8][9] On November 27, 2019, the Padres traded Urías and Eric Lauer to the Milwaukee Brewers in exchange for Trent Grisham, Zach Davies, and cash considerations or a player to be named later.

[13] On April 1, it was announced that Urías had suffered a left hamstring injury on Opening Day and would miss 6–8 weeks.

[15] After struggling to a .145/.299/.236 batting line across 20 games, Urías was optioned to the Triple–A Nashville Sounds on June 29, with Brice Turang being recalled to take his spot.

[18] On August 17, Urías hit the first grand slam of his major-league career, during a Red Sox loss to the Washington Nationals.