Luis de Vargas (1502–1568) was a Spanish painter of the late-Renaissance period, active mainly in Seville.
He traveled to Rome where he was influenced by Mannerist styles.
He painted an altarpiece with multiple panels, including a Virgin and Child appearing to Adam and Eve or La Gamba for the Cathedral in Seville.
He frescoed a Last Judgement for the Casa de Misericordia in Seville.
This article about a Spanish painter is a stub.