Luke Branighan (born 29 June 1981) is an Australian former professional rugby league footballer who played in the 2000s.

He played in the National Rugby League for the St George Illawarra Dragons and Cronulla-Sutherland Sharks, primarily as a five-eighth.

He remained in the first-grade team for the rest of the season, playing in the halves with Trent Barrett.

While playing for NSW Cup side Balmain Tigers in 2005, Branighan was selected to tour with the Malta Knights.

[6] Returning to Australia, Branighan played for Mounties in the Bundaberg Red Cup in 2011.