[8] After sitting out 2015 due to transfer rules, Del Rio was named the starting quarterback for Florida in 2016.

He had also suffered an AC joint sprain in his throwing shoulder earlier in the North Texas game, which hampered his play when he returned from injury.

After struggling in a 31–10 loss against Arkansas on November 5, Del Rio was finally shutdown for the season due to injuries.

[10][11] Del Rio began the 2017 season behind starter Feleipe Franks and top backup Malik Zaire.

[14] In January 2020, Del Rio joined the Washington Football Team to be their offensive quality control coach.

In February 2024, Del Rio was hired by the University of Washington as an offensive analyst under head coach, Jedd Fisch.