During a loss to the Miami Hurricanes in the Gators' second game of the 2013 season, Murphy unsuccessfully attempted a two-point conversion pass.

During the Gators' homecoming loss to the Vanderbilt Commodores, Murphy injured his shoulder, and redshirt freshman quarterback Skyler Mornhinweg played in Florida's final three games.

[5] Murphy immediately flourished at Boston College; his ability as a running quarterback fit in perfectly with Addazio's rush-heavy offense.

He broke the school record for rushing yards by a quarterback (both single-season and career), passing Doug Flutie in only nine games.

He participated in a pre-draft visit with the Pittsburgh Steelers coordinated by agent Nik Visger and was thought to be a possible late round pick.

Pittsburgh has had a noted history of developing college quarterbacks into successful wide receivers, like former players Hines Ward, Kordell Stewart, and Antwaan Randle El.

On November 4, 2015, Pittsburgh Steelers released wide receiver Murphy upon promoting cornerback Doran Grant to their active roster.