Jerram's creation of sculptures, installations, and live art spread internationally since 1997, which by 2022 grew to 104 exhibitions in 25 different countries, visited by over two million people.
[2][dead link] In 2002, he created Tide, an artwork consisting of acoustic sculptures demonstrating 'live' representation of how the moon's gravity affects the Earth, where gravitational information was translated into sound.
[3] In 2004, he began creating a series of transparent and colourless large glass sculptures of viruses and other pathogens, titled Glass Microbiology, recreating viruses such as smallpox, HIV/AIDS, Ebola, hand, foot and mouth disease and swine influenza.
[6] In 2015, he created Withdrawn, which placed a fleet of stranded fishing boats strategically located around Leigh Woods National Nature Reserve.
[8] He is a visiting fellow at the Faculty of Health and Applied Sciences, University of the West of England, Bristol.