Lulu M. Hefner (August 9, 1874 – July 19, 1954) was a Cherokee businessperson from Nowata, Oklahoma who became successful in the oil industry.

[1] Lulu M. Hefner (sometimes spelled Heffner) was a Cherokee businesswoman from Nowata, Oklahoma who opened the first millinery store in that city.

In a 1921 article about her accomplishments, Hefner called the state of Oklahoma "A Happy Hunting Ground" because of its oil reserves and as a nod to her Native American ancestry.

[2] Although Hefner believed that "a woman's judgement beats a man's every time when applied to business," she said she had a collaborative relationship with the oil fraternity and was "always willing to listen to good counsel and advice from the older heads in the oil fields; but depends upon her own business judgment in the last analysis.

"[2] Hefner also managed several side businesses, including a successful motion picture theater and became the owner of the largest garage in Oklahoma.