It provides medical and surgical services for over 350,000 people in southern Bedfordshire, the north of Hertfordshire and parts of Buckinghamshire.

[3] Ten acres of land, situated in the countryside between Luton and Dunstable were purchased from Electrolux and a new hospital was built.

[7] After the facility became a teaching hospital for University College London in March 2012,[8] the Duke of Edinburgh opened a new state-of-the-art cardiac centre there in February 2013.

[14] It was named by the Health Service Journal as one of the top hundred NHS trusts to work for in 2015.

[15] The Care Quality Commission rated Luton and Dunstable Hospital as "good" overall in June 2016.