Łutselkʼe (/ˈlʊtsəlkeɪ/, Dëne Sųłıné Yatıé: [ɬutsʰɛɮk'ɛ]; "place of the łutsel", the cisco,[6] a type of small fish), also spelt Łutsël Kʼé, is a "designated authority"[7] in the North Slave Region of the Northwest Territories, Canada.

[8] Łutselkʼe is a First Nation community and the area was traditionally occupied by the Chipewyan Dene In 1925 the Hudson's Bay Company opened a post followed by the Roman Catholic Church.

[9] There is a proposal ongoing for Thaidene Nene National Park Reserve, with an area of 14,000 km2 (5,400 sq mi), which has the support of the community.

There is a single grocery store, the Lutselk'e Co-op, a post office and nine lodges / outfitters in the area.

Łutsel Kʼe is represented by the Łutsël K'é Dene First Nation and are part of the Akaitcho Territory Government.