The daughter of Johannes Heinrich Guyer, a schoolteacher, she first took interior design courses with Wilhelm Kienzle at the Arts and Crafts School in Zurch (1917) before attending the Technology Institute (1918).
After serving apprenticeships with architectural firms in Zurich and Berlin, she embarked on study trips to Paris, London and Florence.
[1] In 1924, Guyer became one of the first women in Switzerland to establish her own architectural practice, opening an office in Zurich.
When the fair opened the following year in Bern, her reputation was firmly established.
Despite years of war and economic hardship, Guyer continued to run her business under her own name, experiencing an upturn in the 1950s.