LMH provides comprehensive medical, surgical, diagnostic, emergency and support services to a population over 300,000 residents primarily in Adelaide's Northern and North Eastern suburbs.

Trainees receive mentorship from experienced surgeons, benefiting from one-on-one guidance in the operating room, structured feedback, and participation in teaching rounds and case discussions.

In October 2003, Premier Mike Rann and Health Minister Lea Stevens opened new maternity, obstetrics and gynaecology sections, as well as a new women's and children's area.

[3] Stage C of the hospital's redevelopment, included a multi-level staff and visitor car park, completed in 2010, and an additional 96 inpatient beds.

Other improvements in the redevelopment included a helipad facility, teaching and research spaces, a new cardiac catheter laboratory, a second CT scanner and installation of a new MRI machine.