Lyford South is an unincorporated community in Willacy County, Texas, United States.

[3] According to the United States Census Bureau, the former CDP has a total area of 0.2 square mile (0.5 km2), all land.

Prior to the 2010 census, part of this area was annexed to the city of Lyford.

6.1% of all households were made up of individuals, and 2.0% had someone living alone who was 65 years of age or older.

About 39.7% of families and 47.9% of the population were below the poverty line, including 67.0% of those under the age of eighteen and 16.7% of those 65 or over.