The campus served as home to the Lyndon Commercial College from 1886 and in 1910, Theodore Newton Vail, the first president of New England Telephone Company and the American Telephone and Telegraph Company (AT&T) founded the Vermont School of Agriculture on the campus.

[4] Elmer Darling also served as president of the Lyndon Institute's Board of Trustees.

In 1951, the post-secondary programs moved to the newly founded Lyndon State College.

The school has more than 40 domestic and international boarding students, including students from Taiwan, China, Germany, Czech Republic, Sweden, Kazakhstan, Mexico, Vietnam, Canada, Rwanda, Bahamas, Jamaica, Slovenia, and South Korea.

[6] Starting in the 2014–2015 school year, Lyndon Institute expanded curricular opportunities for students with a January Term, in which students take part in a variety of in-depth, project-based learning courses for three weeks.

The school defines the objective of the January Term as: "…to allow every student to create an artifact, or final product, which reflects the acquisition of skill and knowledge in the field of study.

These artifacts will be measured against predefined course requirements and objectives and could include: performances, videos, formal presentations, creation of web page resources, certification in a field, a business plan, a journal, a publication, or a product of some type.

Lyndon Institute is fully accredited by the New England Association of Schools and Colleges[8] and is approved by the Vermont State Agency of Education.

The main building, where all other classes are held, is located on the Darling Campus, along with the auditorium, student services and the administrative offices.

[6] The school's teams compete in Vermont's Division II and in the Mountain League in a variety of sports including football, basketball and baseball for boys, and field hockey, basketball and softball for girls.