[2] While auditioning for a role in Joe (1970) in New York City, Lowry met Lloyd Kaufman, who asked her to appear in a supporting part in The Battle of Love's Return (1971), which she accepted.

[3] She appeared in two key 1970s horror films, George A. Romero's The Crazies (1973)[4] and David Cronenberg's Shivers (1975), followed by a sixteen-month role as the adulterer-heroine Sandra on NBC's short-lived soap opera How to Survive a Marriage, as well as a brief part on the daytime serial Another World.

Lowry moved to Los Angeles in the early 1980s, but ended up abandoning her acting career after appearing in Cat People (1982).

"I wasn’t doing horror movies when I was in Hollywood, I was just going out for TV and other auditions and I got tired so I gave it up; I focused on doing theatre and even sang in a band.

In 2022, Lowry starred as Gina Cochran in Richard Burgin's Fang, for which she won 4 film festival awards.