She graduated from Johns Hopkins University with a Bachelor of Science and a Doctor of Education.

[1] Wiedefeld attended the predecessor to Towson from 1901 to 1904 and served as its seventh president from 1938 to 1947.

[1] She had many roles in Maryland public education, including grade-school teacher from 1914 to 1919.

Afterwards, she worked in Maryland Department of Education from 1919 to 1938, becoming the State Supervisor of Elementary Schools.

[1] Wiedefeld was president during World War II[1] when enrollment declined and employees were hard to obtain.