MASS stands for mitral valve prolapse, aortic root diameter at upper limits of normal for body size, stretch marks of the skin, and skeletal conditions similar to Marfan syndrome.

Treatment options for MASS syndrome are largely determined on a case-by-case basis and generally address the symptoms as opposed to the cause of the disorder.

[6] Other possible symptoms are mitral valve prolapse, a large aortic root diameter, and myopia.

[2] The skeletal features found in MASS syndrome include curvature of the spine (scoliosis), chest wall deformities, and joint hypermobility.

Skin involvement in MASS syndrome is typically limited to stretch marks (striae distensae).