3CKK423417299ENSG00000037897ENSMUSG00000006732Q9UBP6Q9Z120NM_005371NM_023032NM_023033NM_010792NP_005362NP_075422NP_034922tRNA (guanine-N(7)-)-methyltransferase is an enzyme that in humans is encoded by the METTL1 gene.

[5][6] This gene is similar in sequence to the S. cerevisiae YDL201w gene.

The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.

Alternative splice variants encoding different protein isoforms and transcript variants utilizing alternative polyA sites have been described in the literature.

This article on a gene on human chromosome 12 is a stub.