In this new setting, Mickey Mouse has a hard life, because he has no friends and because the authors wanted to break traditional cliché of his adventures in Mouseton, featured in Italian comic Topolino.

Villains are different from Black Pete and even from Phantom Blot, often unsuspected, and even friends act in a rude way toward Mickey Mouse, who often feels disoriented in the big city.

To prove his innocence, being mistaken for a criminal, both by Anderville villains and police inspector Jan Clayton, he faces some dangerous situations, running the risk of being killed.

They created Anderville, through many sketches and decided on a specific range of colors to use for the stories, preferring the dark and cold tones to the light and warm ones.

MM demonstrated the talent of Francesco Artibani and Tito Faraci, main writers of the series, and was a showcase for the talent of some young, at the time, drawers: Silvio Camboni, Corrado Mastantuono, Paolo Mottura, Marco Palazzi, Alessandro Perina, Claudio Sciarrone, Stefano Turconi, Silvia Ziche and Giuseppe Zironi.